Owner Scorecard


← All companies ← PLUS Manual PLXS → ← PLUR Biotechnology PRME →

PLX, Protalix BioTherapeutics Inc. (DE)

Biotechnology consumer brand

We are a commercial stage biopharmaceutical company focused on the discovery, development, production and commercialization of innovative therapeutics for rare diseases with significant unmet needs.

ProCellEx , our unique, proprietary plant cell-based protein expression system represents a new method for developing recombinant proteins in an industrial-scale manner.

To execute on our strategy, we are turning our focus to new, early-stage product candidates that treat indications for which there are high unmet needs in terms of efficacy and safety, including renal diseases.

Latest annual: FY2025 10-K
PLX · Protalix BioTherapeutics Inc. (DE)
I

The business

What it sells, where the money comes from, the kind of company it is.

Revenue · FY2025
$53M
−1.2% YoY · −3% 5-yr CAGR
Vital signs · TTM, with 5-yr average
Revenue $81M 5-yr avg $52M
Gross margin 69% 5-yr avg 57%
Operating margin 28.9% 5-yr avg −13.6%
ROIC 43% 5-yr avg −564%
Owner-earnings margin 10% 5-yr avg −20%
Free cash flow margin 10% 5-yr avg −20%

Next report By 11/13 · the 10-Q for the quarter ended late September · due within 45 days of period end · has filed ~44 days after · the wire records it on arrival

The business in brief

read the 10-K →

What this business is and what moves its needle, from its own SEC filings.

What moves the needle
Operating margin has reached 16% at its best but run negative through the cycle (median −23%) on a 59% gross margin — so the question is which reading is truer: whether the median was pulled below zero by one-off charges, by the cycle, or by spending it is still growing into, and whether it settles back at a profit. Inventory runs near 35% of sales, so how fast it turns back into cash — and the risk of writing it down when demand softens — sits alongside the margin. Read this kind of business on the pipeline against the patent cliff, and pricing. On its own account, the filing leans hardest on pricing power & competition, set against the numbers in what the filing emphasizes, below.
Is it a good business?
Return on capital has rarely cleared the cost of capital (median −1%, above 15% in 1 of 4 years). Owner earnings, the cash-based check, have been thin too. This is price-taker territory, where the balance sheet and the cycle matter more than any multiple; the rest is in the 10-K.

Every line is arithmetic on the company's filings, shown in full in the sections below.

II

The record

Ten years of arithmetic, read across the cycle.

The record, 2016–2025

realized figures from each filing · older years to the left
2016’162017’172018’182019’192020’202021’212022’222023’232024’242025’25TTMTTMJun 2026
Income statement
$9M$21M$34M$55M$63M$38M$48M$65M$53M$53M$81MRevenueRevenue
$801K$25M$44M$52M$22M$28M$43M$29M$26M$56MGross profitGross prof.
9%73%80%83%57%59%65%54%49%69%Gross marginGross mgn
102%55%32%18%18%33%25%23%23%22%16%SG&A / revenueSG&A/rev
331%153%97%82%61%78%62%26%24%37%25%R&D / revenueR&D/rev
($33M)($35M)($19M)($11M)$3M($20M)($13M)$10M$4M($6M)$23MOperating incomeOp. inc.
−360.5%−163.8%−56.4%−19.6%4.3%−53.4%−27.3%16.0%7.3%−10.4%28.9%Operating marginOp. mgn
($7M)($28M)($14M)$9M$4M($6M)Pretax incomePretax
($29M)($83M)($26M)($18M)($7M)($28M)($15M)$8M$3M($7M)$19MNet incomeNet inc.
3%29%19%Effective tax rateTax rate
Cash flow & returns
($32M)($10M)($8M)($19M)($26M)($10M)($25M)($1M)$9M($12M)$10MOperating cash flowOp. cash
$2M$2M$2M$2M$1M$1M$1M$1M$1M$1M$2MDepreciationDeprec.
($6M)$71M$17M($4M)($24M)$14M($13M)($14M)$1M($9M)($13M)Working capital & otherWC & other
$849K$971K$686K$627K$655K$1M$628K$1M$1M$2M$2MCapexCapex
9.2%4.6%2.0%1.1%1.0%3.8%1.3%1.8%2.4%3.1%2.8%Capex / revenueCapex/rev
($33M)($11M)($8M)($20M)($27M)($11M)($26M)($2M)$7M($14M)$8MOwner earningsOwner earn.
−358.2%−52.0%−24.6%−36.5%−42.5%−29.7%−53.8%−3.8%13.8%−25.8%10.4%Owner earnings marginOE mgn
($33M)($11M)($8M)($20M)($27M)($12M)($26M)($2M)$7M($14M)$8MFree cash flowFCF
−358.2%−52.0%−24.6%−36.5%−42.5%−30.6%−53.8%−3.8%13.8%−25.8%9.5%Free cash flow marginFCF mgn
($967K)($1M)($591K)($883K)($20M)$19M($5M)($17M)$4M($2M)Investing cash flowInv. cash
$20M($1M)($5M)$0$46M$12M$8M$25M($17M)$9MFinancing cash flowFin. cash
$277K$414K($270K)$225K$64K$6K($77K)($114K)$25K($47K)Exchange-rate effectFX
($13M)($12M)($13M)($20M)$473K$21M($22M)$7M($4M)($5M)Change in cashΔ cash
-2358%102%12%-13%43%ROICROIC
25%7%-14%27%Return on equityROE
25%7%−14%27%Retained to equityRetained/eq
Balance sheet
$63M$51M$38M$18M$18M$39M$17M$24M$20M$15M$27MCash & investmentsCash+inv
$693K$2M$5M$5M$2M$3M$5M$5M$3M$9M$17MReceivablesReceiv.
$5M$8M$9M$8M$13M$18M$17M$19M$21M$26M$32MInventoryInvent.
$7M$9M$10M$12M$14M$16M$12M$20M$5M$5M$7MAccounts payablePayables
($2M)$244K$3M$950K$1M$5M$9M$5M$20M$29M$42MOperating working capitalOper. WC
$72M$63M$53M$32M$56M$62M$45M$70M$60M$67M$92MCurrent assetsCur. assets
$66M$23M$25M$40M$86M$33M$32M$46M$26M$27M$31MCurrent liabilitiesCur. liab.
1.1×2.8×2.1×0.8×0.6×1.9×1.4×1.5×2.3×2.5×2.9×Current ratioCurr. ratio
$9M$8M$6M$5M$5M$5M$5M$5M$5M$5MNet PP&ENet PP&E
$82M$72M$61M$45M$68M$74M$56M$84M$73M$82M$110MTotal assetsAssets
$19M$46M$48M$51M$28M$28MTotal debtDebt
($44M)($5M)$10M$33M($11M)$11MNet debt / (cash)Net debt
$92M$102M$114M$116M$95M$80M$66M$51M$30M$34MTotal liabilitiesTotal liab.
($10M)($29M)($53M)($70M)($27M)($6M)($11M)$34M$43M$48M$71MShareholders’ equityEquity
10.7%1.6%1.5%1.5%5.0%6.2%4.4%5.3%6.1%4.4%2.8%Stock comp / revenueSBC/rev
Per share
203M26.2M29.4M29.7M29.1M44.1M48.5M82.4M81.1M78.5M82.8MShares out (diluted)Shares
$0.05$0.80$1.16$1.84$2.16$0.87$0.98$0.79$0.66$0.67$0.97Revenue / shareRev/sh
$-0.14$-3.18$-0.90$-0.62$-0.22$-0.62$-0.31$0.10$0.04$-0.08$0.23EPS (diluted)EPS
$-0.16$-0.42$-0.29$-0.67$-0.92$-0.26$-0.53$-0.03$0.09$-0.17$0.10Owner earnings / shareOE/sh
$-0.16$-0.42$-0.29$-0.67$-0.92$-0.27$-0.53$-0.03$0.09$-0.17$0.09Free cash flow / shareFCF/sh
$0.00$0.04$0.02$0.02$0.02$0.03$0.01$0.01$0.02$0.02$0.03Cap. spending / shareCapex/sh
$-0.05$-1.12$-1.80$-2.37$-0.93$-0.14$-0.22$0.41$0.53$0.61$0.86Book value / shareBVPS

The diluted share count moved ×1/7.73 into 2017 — shares retired, not a split the totals corroborate — and the per-share figures carry the counts as filed.

Share counts before 2020 are restated ×2 for a stock split, so per-share figures sit on one basis.

The diluted share count moved ×1.51 into 2021 — shares issued, not a split the totals corroborate — and the per-share figures carry the counts as filed.

The diluted share count moved ×1.7 into 2023 — shares issued, not a split the totals corroborate — and the per-share figures carry the counts as filed.

Per-share growththe realized rate an owner's share compounded
9-yr5-yr
Revenue / share+34.9%/yr−20.8%/yr
Capital spending / share+19.5%/yr−1.5%/yr

Net income is the accountant's number; owner earnings is the cash an owner could take out. The walk between them, off the cash-flow statement, and whether the gap is widening or holding.

In fiscal 2025 the business reported a $7M loss but ($14M) of owner earnings: $7M less than the profit line, taken out by capital spending and the timing of cash.

FY2025FY2024FY2023FY2022FY2021
Reported net income($7M)$3M$8M($15M)($28M)
Depreciationnon-cash charge added back+$1M+$1M+$1M+$1M+$1M
Stock-based compensationreal costnon-cash, but a real cost+$2M+$3M+$3M+$2M+$2M
Working capital & othertiming of cash in and out, other non-cash items−$9M+$1M−$14M−$13M+$14M
Cash from operations($12M)$9M($1M)($25M)($10M)
Maintenance capital expenditurethe spending needed just to hold position and volume−$2M−$1M−$1M−$628K−$1M
Owner earnings($14M)$7M($2M)($26M)($11M)
Growth capital expenditurediscretionary; spent to get bigger, not to stand still−$341K
Free cash flow($14M)$7M($2M)($26M)($12M)
Owner-earnings marginowner earnings ÷ revenue-26%14%-4%-54%-30%

Owner earnings is the cash an owner could pull out without starving the business: operating cash less the capital it must spend to hold its position . The cash-flow statement also adds stock comp back as non-cash, but it is a real cost paid in shares; counted as the expense it is (less $2M), owner earnings is nearer ($16M).

Maintenance capex is estimated as depreciation where a growing business invests above it; free cash flow is the figure the scorecard's free-cash margin reads.

III

Quality & stewardship

Returns, the balance sheet, capital allocation, and pay.

Owner’s Scorecard

FY2025 10-K · source on SEC EDGAR →

Will it survive?

  • Interest expense not tagged in the data
    What this means

    No usable interest-expense line was tagged in the filing data, but the balance sheet carries real net debt — so the interest burden here is unknown, not absent. Read the debt on the net-debt check below.

  • Net debt against an operating loss
    Cash $15M − debt $28M
    What this means

    Netting $15M of cash and short-term investments against $28M of debt leaves $14M owed, with no operating profit this year to measure it against — understand that combination before anything else about the company. Net debt is the leverage figure that matters: the cash is already set against the debt. Strategic or illiquid investments aren't counted here.

  • Long (60+ days)
    DSO 61 + DIO 348 − DPO 71 days
    What this means

    Days cash is tied up between paying suppliers and collecting from customers. Lower is better; a long cycle means growth itself eats cash.

Is it a good business?

  • Below average through the cycle
    4-yr median, range -2358%–102%; -7% latest = NOPAT ($4M) ÷ invested capital $62M
    Industry peers: median -45%
    What this means

    The rate the business earns on the money tied up in it, Buffett's north star, because over time a stock tracks the ROIC beneath it. Above ~15% sustained hints at a moat; a return below the cost of capital (~8%) erodes value as a business grows rather than building it — the test Buffett weighs most. The headline is the median of the last 4 years (it ran -7% most recently), so one peak or trough year doesn't set the verdict. Asset-light businesses (R&D expensed, little capital) read artificially high, pair this with Owner Earnings.

  • Consumes cash through the cycle
    10-yr median margin, range -358%–14%; latest ($14M) = operating cash ($12M) − maintenance capex $2M
    Industry peers: median -256%
    What this means

    What an owner could take out without starving the business: operating cash less the maintenance capital it must spend to hold its position — Buffett's owner earnings. That's -26% of revenue this year, a -33% median across 10 years. Treating stock comp as the real expense it is (less $2M of SBC) leaves ($16M).

  • Loss, and burning cash
    Net income ($7M) · cash from operations ($12M)

    In the filing’s words Read against the cash, reported earnings have run ahead of the operating cash the business generated over the record, and a manipulation screen of eight balance-sheet ratios trips on it. For an inventory- or content-heavy grower that can be cash tied up in real assets as it expands; elsewhere it can mean the earnings lean on accounting estimates — the cash-flow statement against the income statement is where to tell which.

    What this means

    The company reported a net loss, so a conversion ratio isn't meaningful. What matters then is whether operations still threw off cash, here, they did not.

How is the cash used?

  • Not enough data
    What this means

    The filing data didn't include the inputs for this check.

  • Investing or harvesting? 1.12×
    Maintaining
    Capex $2M ÷ property depreciation $1M
    What this means

    Descriptive, not a grade. Above ~1× means investing faster than assets wear out (growth, or, sustained for years, today's earnings carrying less depreciation than tomorrow's will). Below means spending less than it's wearing out (efficiency, or a melting asset base). The ratio won't tell you which; the filings will.

The promise and the pay packet

  • Is the buyback buying ownership, or mopping up? 4.4%
    Stock pay, share count unread
    Stock compensation $2M (fiscal 2025), 4.4% of revenue · no repurchases · the share count is not comparable across these years (a split or a first listing sits in the record), so the drift is withheld
    What this means

    Stock handed to employees is a real cost paid in the owner's own currency: it is charged against profit, but the shares it creates are permanent. Many companies repurchase stock at the same time, which looks like a return of capital and often is not — if the count barely moves, the cash merely cancelled the pay packet and bought the owner nothing. The three states worth telling apart are a count genuinely shrinking, a count standing still despite large repurchases, and a count rising because the issuance was never offset at all.

Graham’s defensive tests · 2 of 4 met

Graham’s numerical criteria for the defensive investor (The Intelligent Investor, ch. 14), run on the filings. A floor of safety, not a buy signal; many fine modern businesses fail his strictest liquidity rules by design.

  • Adequate size Miss
    Revenue ≥ $2B · $53M
    What this means

    Big enough to weather a storm. Graham's 1972 floor was ~$100M of sales (≈ $700M today); we use a $2B revenue line as a conservative modern stand-in.

  • Strong liquidity Pass
    Current ratio ≥ 2× · 2.51×
    What this means

    Current assets at least twice current liabilities, near-term bills covered without touching the business. Strict by design: many cash-rich modern firms run leaner and miss it, holding their cushion in longer-dated securities.

  • Conservative debt Pass
    Debt ≤ working capital · $28M vs $40M WC
    What this means

    Graham's rule that borrowings not exceed net current assets. Capital-heavy and buyback-heavy firms routinely fail it, read it next to interest coverage, not alone.

  • Earnings stability Miss
    A profit every year (10-yr record) · 8 loss years
    What this means

    Graham wanted earnings in each of the past ten years, the stability a defensive owner leans on.

  • Dividend record
    Uninterrupted dividends · no dividend line tagged in the data
    What this means

    An unbroken dividend was Graham's mark of durability. This record carries no dividends-paid line in any year — common for partnerships, whose distributions file under tags the chain doesn't read — so the criterion is withheld rather than judged on silence.

  • Earnings growth
    Earnings +33% over the record ·
    What this means

    Earnings were negative early in the record, a growth rate isn't meaningful.

  • Moderate price
    P/E ≤ 15 and P/E × P/B ≤ 22.5 · decided by the price
    What this means

    Graham's valuation gate, the wall he kept between a sound business and a sound investment. Three-year average earnings are $0.02/share (latest year $-0.08), the averaged base the calculator's gate runs on, and book value is $0.60/share. Enter a price in “What the price implies” just below for the P/E, P/B, and whether it clears. But this is the rule Buffett outgrew: there's no hard P/E law, and a wonderful business can deserve a far richer multiple if the thesis holds, treat it as the bargain-hunter's floor, not a verdict on the price.

Durability & moat, 2016–2025

Whether the record’s returns held, and what the capital reinvested earned.

  • Profitable years 2 of 10
    What this means

    Lost money in 8 year(s), look at what happened there before trusting the average.

  • Operating margin −194% → 4% (3-yr avg ends)
    What this means

    Through the cycle the operating margin widened — about −194% early to 4% lately, median −27% — pricing power intact or improving.

  • Reinvestment, incremental ROIC returns capital
    What this means

    The capital base barely grew: this business returns cash through dividends and buybacks rather than reinvesting. Judge it on the cash returned, not on compounding.

  • Worst year 2016 · −360.5% op. margin
    What this means

    Operations went underwater in 2016, understand why before trusting the good years.

  • Share count −2.8%/yr
    What this means

    The share count is shrinking, buybacks are quietly growing your slice of the business.

All figures as filed; the source filing is linked above.

Current Position

as of the latest quarter, Jun 30, 2026

Can the business pay what it owes this year, off the freshest balance sheet: the quality of the assets, the debt actually coming due, and what a low ratio means here.

Current assets$92M
  • Cash & short-term investments$27M
  • Receivables$17M
  • Inventory$32M
  • Other current assets$16M
Current liabilities$31M
  • Accounts payable$7M
  • Other current liabilities$25M
Current ratio2.94×all current assets ÷ what's due · Graham looked for 2×
Quick ratio1.91×stricter: inventory excluded
Cash ratio0.87×strictest: cash alone against what's due
Working capital$61Mthe cushion left after near-term bills
Revenue, latest quarter vs. a year ago+27.1%the freshest read on whether the business is still growing
Current ratio, recent quarters2.0× → 2.9×
Deeper floors
Tangible book value$71Mequity stripped of goodwill & intangibles
Net current asset value$53MGraham's net-net: current assets less all liabilities
Debt incl. operating leases$9M$9M of it operating leases

From the company's latest filing.

Management, ownership & pay

read the proxy →

From the proxy: how much of the business the people running it own, and how they are paid, beside what the business earned for its owners in the same years.

Fiscal yearChief executivePay, as filed“Actually paid”Owner earnings
2023Mr. Bashan$2.7M$3.2M($2M)
2024Mr. Bashan$1.5M$525k$7M
2025Mr. Bashan$1.2M$1.5M($14M)

Both pay figures are the company’s own, from the pay-versus-performance table its proxy statement files. “As filed” is the Summary Compensation Table total: salary, bonus, and equity awards at their value on the day of grant. “Actually paid” is the SEC’s prescribed recalculation, which re-marks those equity awards to what they became as they vested; it can swing far above or below the filed figure in either direction, and negative years occur. Owner earnings are the whole business's, from the record above, for the same fiscal years.

  • Insider ownership<1%

    The stake all directors and executive officers hold together, per the 2026 proxy: skin in the game, the first thing Munger reads.

  • Stock-based compensation$2M

    The slice of the business handed to employees in shares in fiscal 2025, 4.4% of revenue. Buffett's oldest accounting fight: this is compensation, compensation is an expense, real whether or not the headline earnings admit it. One trap: the cash-flow statement adds SBC back, so the operating cash, and the owner earnings drawn from it, are flattered by exactly this amount; counted as the cost it is, what an owner keeps is lower.

Peers, Biotechnology

The same industry, side by side on owner economics. Each column names the period it is read over, and a median resting on fewer than three years carries that count beside it; the group median at the foot is the line to read each figure against.

CompanyRevenuelatest FY, USDGross marginmedian over the recordOp. marginmedian over the recordROICmedian over the recordOwner earn. marginmedian over the record
RXRXRecursion Pharmaceuticals Inc.$75M5%-799.7%-106%-570%
CLLSCellectis S.A.$73M25%3y-341.0%-206%-217%
CGENCompugen Ltd.$73M88%-92.0%-37%-92%
VIRVir Biotechnology Inc.$69M95%4y-544.0%-45%-417%
MESOMesoblast Limited$65M70%1y-488.4%-11%-571%2y
PLXProtalix BioTherapeutics Inc. (DE)$53M59%-23.5%-1%4y-33%
KYMRKymera Therapeutics Inc.$39M0%-277.5%-26%-256%
CCCCC4 Therapeutics Inc.$36M-336.1%-50%-276%
Group median59%-338.6%-41%-266%
IV

The price

What a price has to assume.

What the price implies

reverse-DCF

Type today's close and see the owner-earnings growth you'd have to believe to justify it, beside what Protalix BioTherapeutics Inc. (DE) has delivered.

$
Base

The assumptions

9.0% = the 4.65% 10-year Treasury (Aug 19, 2026) + 4.35 points of equity premium. The rate you require is yours to set.

Enter a price above to run it.

Implied by the price
Owner-earnings growth, delivered
Owner-earnings yield
P/E (3-yr earnings ’23–’25)
P/B
Graham’s price gate

Graham capped the multiple at 15×; Buffett and Munger let that rule go: a wonderful business can deserve 50× if the thesis holds. The gate marks the bargain-hunter's floor.

Against a high-grade bond: Graham’s yardstick bond yield%

Prefilled with the 10-year Treasury (4.65%, as of Aug 19, 2026). Edit it for today’s exact figure, or a AAA corporate yield.

Graham measured a stock against the bond you could own instead, the heart of his margin of safety. Enter a price above to weigh the owner-earnings yield against this bond.

Free cash flow $8M on 81M shares outstanding, per the 10-Q cover, as of 2026-08-01; net cash $27M. The base is the latest year by default; Normalize values it on the through-cycle median owner-earnings margin (to avoid paying on a peak year). Net of stock comp treats option pay as the expense it is. Capex ($2M) runs well above depreciation ($2M), so this is a build-out; Steady-state swaps total capex for maintenance (≈ depreciation), lifting the base to about $8M, the cash it would throw off if it stopped expanding. The dials set the multiple a growth belief justifies; the price, and every dollar on this page, is yours.

Cite: Owner Scorecard, "Protalix BioTherapeutics Inc. (DE) (PLX), the owner's record," https://ownerscorecard.com/c/PLX, data as of 2026-08-17.

Manual order: ← PLUS its page in the Manual PLXS →

Industry order: ← PLUR the Biotechnology chapter PRME →